Subgroup effects despite homogeneous heterogeneity test results

Subgroup effects despite homogeneous heterogeneity test results

BACKGROUND Statistical tests of heterogeneity are very popular in meta-analyses, as heterogeneity might indicate subgroup effects. Lack of demonstrable statistical heterogeneity, however, might obscure clinical heterogeneity, meaning clinically relevant subgroup effects. METHODS A qualitative, visual method to explore the potential for subgroup effects was provided by a modification of the fo...

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[Drug effects on laboratory test results].

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Effects of Tonsil size on Pulmonary Function test Results after Tonsillectomy in Children

Introduction: Adenotonsillar hypertrophy is a typical cause of surgery in children. Evaluation and identification of patients as potential candidates tonsillectomy is a primary concern for otolaryngologists. This study focuses on the results of pulmonary function tests (PFTs) after tonsillectomy in children. Materials and Methods: This cross-sectional study examined 50 patients suffering from t...

The Value of Heterogeneity for Cost-Effectiveness Subgroup Analysis

This article develops a general framework to guide the use of subgroup cost-effectiveness analysis for decision making in a collectively funded health system. In doing so, it addresses 2 key policy questions, namely, the identification and selection of subgroups, while distinguishing 2 sources of potential value associated with heterogeneity. These are 1) the value of revealing the factors asso...